Carbidopa: Difference between revisions
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== Carbidopa == | == Carbidopa == | ||
<StructureSection load='1js3' size='340' side='right' caption='Crystal structure of DOPA Decarboxylase in complex with the inhibitor carbidopa PDB:[[1js3]]' scene=''> | <StructureSection load='1js3' size='340' side='right' caption='Crystal structure of DOPA Decarboxylase in complex with the inhibitor carbidopa PDB:[[1js3]]' scene=''> | ||
<scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4 | <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | ||
== Function == | == Function == | ||
<scene name='pdbligand=142:CARBIDOPA'>Carbidopa</scene> inhibits aromatic-L-amino-acid decarboxylase (DOPA Decarboxylase or DDC)<ref name="one">PMID:11106255</ref> | <scene name='pdbligand=142:CARBIDOPA'>Carbidopa</scene> inhibits aromatic-L-amino-acid decarboxylase ([[DOPA Decarboxylase]] or DDC)<ref name="one">PMID:11106255</ref> by binding to the <scene name='74/746001/Active_site_dopa/4'>active site</scene> | ||
== Disease == | == Disease == | ||
