Sandbox 54321: Difference between revisions

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<scene name='74/745973/Lisinopril_zinc/1'>Lisinopril</scene>is a synthetic angiotensin-converting enzyme inhibitor (ACE inhibitors) with molecular formula of C21+H31+N3+O5, empirical formula of C21+H31+N3+O5*2H2O, and average molecular weight of 405.495 g/mol. It is primarily used for the treatment of hypertension<ref name="four">National Center for Biotechnology Information. PubChem Compound Database; CID=5362119, https://pubchem.ncbi.nlm.nih.gov/compound/5362119 (accessed Nov. 12, 2016).</ref>. Lisinopril is typically in the trans isometric form because it has a lower steric repulsion between the hydroxyl and carboxyl groups than the cis conformation and is biologically active in this form <ref name= "five">Bouabdallah, S., Dhia, T. B., & Driss, R. (2014, February 25). Study of a Conformational Equilibrium of Lisinopril by HPLC, NMR, and DFT. Retrieved November 12, 2016, from https://www.hindawi.com/journals/ijac/2014/494719/
<scene name='74/745973/Lisinopril_zinc/1'>Lisinopril</scene>is a synthetic angiotensin-converting enzyme inhibitor (ACE inhibitors) with molecular formula of C21+H31+N3+O5, empirical formula of C21+H31+N3+O5*2H2O, and average molecular weight of 405.495 g/mol. It is primarily used for the treatment of hypertension<ref name="four">National Center for Biotechnology Information. PubChem Compound Database; CID=5362119, https://pubchem.ncbi.nlm.nih.gov/compound/5362119 (accessed Nov. 12, 2016).</ref>. Lisinopril is typically in the trans isometric form because it has a lower steric repulsion between the hydroxyl and carboxyl groups than the cis conformation and is biologically active in this form <ref name= "five">Bouabdallah, S., Dhia, T. B., & Driss, R. (2014, February 25). Study of a Conformational Equilibrium of Lisinopril by HPLC, NMR, and DFT. Retrieved November 12, 2016, from https://www.hindawi.com/journals/ijac/2014/494719/
</ref>.Lisinopril has a benzene ring and from there it has a 4-carbon amide chain where it branches of into a carboxylic acid group one way and a secondary amide group the other way which connects to the rest of the molecule. From the secondary amide, the molecule branches into a 5-carbon amine with a primary amide at the end. The other branch from the secondary amide has a ketone bonded to a nitrogen in a 4-carbon ring. From this carbon ring, there is a carboxylic acid group.
</ref>.Lisinopril has a benzene ring and from there it has a 4-carbon amide chain where it branches of into a carboxylic acid group one way and a secondary amide group the other way which connects to the rest of the molecule. From the secondary amide, the molecule branches into a 5-carbon amine with a primary amide at the end. The other branch from the secondary amide has a ketone bonded to a nitrogen in a 4-carbon ring. From this carbon ring, there is a carboxylic acid group.
== Structural highlights ==
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.


== Mechanism ==
== Mechanism ==
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