5ejh: Difference between revisions
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==Crystal structure of NAD kinase V98S mutant from Listeria monocytogenes== | |||
<StructureSection load='5ejh' size='340' side='right' caption='[[5ejh]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ejh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EJH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EJH FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_kinase NAD(+) kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.23 2.7.1.23] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ejh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ejh OCA], [http://pdbe.org/5ejh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ejh RCSB], [http://www.ebi.ac.uk/pdbsum/5ejh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ejh ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/NADK1_LISMO NADK1_LISMO]] Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.[HAMAP-Rule:MF_00361]<ref>PMID:17686780</ref> <ref>PMID:22608967</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Assairi, L]] | |||
[[Category: Gelin, M]] | |||
[[Category: Labesse, G]] | [[Category: Labesse, G]] | ||
[[Category: Pochet, S]] | [[Category: Pochet, S]] | ||
[[Category: Poncet-Montange, G]] | [[Category: Poncet-Montange, G]] | ||
[[Category: | [[Category: Allostery]] | ||
[[Category: Citrate]] | |||
[[Category: Gram-positive nad kinase]] | |||
[[Category: Transferase]] | |||
Revision as of 19:45, 9 December 2016
Crystal structure of NAD kinase V98S mutant from Listeria monocytogenes
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