5en4: Difference between revisions
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==Complex of 17-beta-hydroxysteroid dehydrogenase type 14 with inhibitor.== | |||
<StructureSection load='5en4' size='340' side='right' caption='[[5en4]], [[Resolution|resolution]] 1.52Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5en4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EN4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EN4 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5Q6:[2,3-BIS(OXIDANYL)PHENYL]-[6-(2-FLUORANYL-3-OXIDANYL-PHENYL)PYRIDIN-2-YL]METHANONE'>5Q6</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1yde|1yde]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5en4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5en4 OCA], [http://pdbe.org/5en4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5en4 RCSB], [http://www.ebi.ac.uk/pdbsum/5en4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5en4 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/DHB14_HUMAN DHB14_HUMAN]] Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).<ref>PMID:17067289</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bertoletti, N]] | |||
[[Category: Braun, F]] | [[Category: Braun, F]] | ||
[[Category: Heine, A]] | |||
[[Category: Klebe, G]] | |||
[[Category: Marchais-Oberwinkler, S]] | [[Category: Marchais-Oberwinkler, S]] | ||
[[Category: | [[Category: Inhibitor complex]] | ||
[[Category: | [[Category: Oxidoreductase]] | ||
[[Category: | [[Category: Steroid dehydrogenase]] | ||
Revision as of 10:47, 10 December 2016
Complex of 17-beta-hydroxysteroid dehydrogenase type 14 with inhibitor.
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