1qvn: Difference between revisions

Revision as of 20:19, 30 March 2008

1qvn, resolution 2.70Å

Ligands:

FRI, ZN

Gene:

IL2 (Homo sapiens)

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

Structure of SP4160 Bound to IL-2 V69A

Known disease associated with this structure: Severe combined immunodeficiency due to IL2 deficiency OMIM:[147680]

1QVN is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Sun Mar 30 23:19:36 2008

@@ Line 4: / Line 4: @@
 |PDB= 1qvn |SIZE=350|CAPTION= <scene name='initialview01'>1qvn</scene>, resolution 2.70&Aring;
 |SITE=
-|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=FRI:2-GUANIDINO-4-METHYL-PENTANOIC ACID [2-(4-{5-[4-(4-ACETYLAMINO-BENZYLOXY)-2,3-DICHLORO-PHENYL]-2-METHYL-2H-PYRAZOL-3-YL}-PIPERIDIN-1-YL)-2-OXO-ETHYL]-AMIDE'>FRI</scene>
+|LIGAND= <scene name='pdbligand=FRI:2-GUANIDINO-4-METHYL-PENTANOIC+ACID+[2-(4-{5-[4-(4-ACETYLAMINO-BENZYLOXY)-2,3-DICHLORO-PHENYL]-2-METHYL-2H-PYRAZOL-3-YL}-PIPERIDIN-1-YL)-2-OXO-ETHYL]-AMIDE'>FRI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
 |ACTIVITY=
 |GENE= IL2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+|DOMAIN=
+|RELATEDENTRY=
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qvn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qvn OCA], [http://www.ebi.ac.uk/pdbsum/1qvn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1qvn RCSB]</span>
 }}
@@ Line 22: / Line 25: @@
 [[Category: Thanos, C D.]]
 [[Category: Wells, J A.]]
-[[Category: FRI]]
-[[Category: ZN]]
 [[Category: il-2 small molecule hot spot]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:43:17 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:19:36 2008''