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'''Unreleased structure'''


The entry 5lev is ON HOLD  until Aug 25 2017
==Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant)==
 
<StructureSection load='5lev' size='340' side='right' caption='[[5lev]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
Authors: Pike, A.C.W., Dong, Y.Y., Chu, A., Tessitore, A., Goubin, S., Dong, L., Mukhopadhyay, S., Mahajan, P., Chalk, R., Berridge, G., Wang, D., Kupinska, K., Belaya, K., Beeson, D., Burgess-Brown, N., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5lev]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LEV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LEV FirstGlance]. <br>
Description: Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant)(CASP target)
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine--dolichyl-phosphate_N-acetylglucosaminephosphotransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.8.15 2.7.8.15] </span></td></tr>
[[Category: Goubin, S]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lev OCA], [http://pdbe.org/5lev PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lev RCSB], [http://www.ebi.ac.uk/pdbsum/5lev PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lev ProSAT]</span></td></tr>
[[Category: Pike, A.C.W]]
</table>
== Disease ==
[[http://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN]] DPAGT1-CDG;Congenital myasthenic syndromes with glycosylation defect. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.  
== Function ==
[[http://www.uniprot.org/uniprot/GPT_HUMAN GPT_HUMAN]] Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.  
__TOC__
</StructureSection>
[[Category: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase]]
[[Category: Arrowsmith, C H]]
[[Category: Beeson, D]]
[[Category: Belaya, K]]
[[Category: Berridge, G]]
[[Category: Bountra, C]]
[[Category: Burgess-Brown, N]]
[[Category: Burgess-Brown, N]]
[[Category: Wang, D]]
[[Category: Carpenter, E P]]
[[Category: Chalk, R]]
[[Category: Chu, A]]
[[Category: Chu, A]]
[[Category: Mukhopadhyay, S]]
[[Category: Dong, L]]
[[Category: Berridge, G]]
[[Category: Dong, Y Y]]
[[Category: Carpenter, E.P]]
[[Category: Edwards, A M]]
[[Category: Bountra, C]]
[[Category: Goubin, S]]
[[Category: Kupinska, K]]
[[Category: Kupinska, K]]
[[Category: Dong, L]]
[[Category: Arrowsmith, C.H]]
[[Category: Chalk, R]]
[[Category: Dong, Y.Y]]
[[Category: Mahajan, P]]
[[Category: Mahajan, P]]
[[Category: Mukhopadhyay, S]]
[[Category: Pike, A C.W]]
[[Category: Structural genomic]]
[[Category: Tessitore, A]]
[[Category: Tessitore, A]]
[[Category: Edwards, A.M]]
[[Category: Wang, D]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Congenital myasthenic syndrome 13]]
[[Category: Beeson, D]]
[[Category: Integral membrane protein]]
[[Category: Belaya, K]]
[[Category: Protein glycosylation]]
[[Category: Sgc]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/5lev"