Methotrexate: Difference between revisions

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[[Methotrexate]], formerly known as amethopterin, is a drug that is used in the competitive inhibition of [[Dihydrofolate reductase]], resulting in decreased synthesis of dTTP and diminished cellular replication. The antimetabolic nature of methotrexate is most effective against the most rapidly dividing cells, making this drug useful in [[Cancer]] [[Pharmaceutical Drugs|treatment]], and various autoimmune diseases<ref>Methotrexate. (n.d.). UW Department of Orthopaedics and Sports Medicine - Patient Care. Retrieved March 10, 2011, from http://www.orthop.washington.edu/PatientCare/OurServices/Arthritis/Articles/Methotrexate.aspx </ref>.

Methotrexate: Difference between revisions

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Revision as of 11:43, 15 January 2017 view source Joel L. Sussman (talk \| contribs) ConfirmAccount, Editor, Mutation, Print3D, Tester, Bureaucrats, journal 11,524 edits No edit summary ← Older edit		Revision as of 14:55, 15 January 2017 view source Joel L. Sussman (talk \| contribs) ConfirmAccount, Editor, Mutation, Print3D, Tester, Bureaucrats, journal 11,524 edits No edit summary Newer edit →
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	<StructureSection load='2w3m' size='~~300~~' side='right' scene='42/420816/Cv/2' caption=''>		<StructureSection load='2w3m' size='450' side='right' scene='42/420816/Cv/2' caption=''>
	[[Methotrexate]], formerly known as amethopterin, is a drug that is used in the competitive inhibition of [[Dihydrofolate reductase]], resulting in decreased synthesis of dTTP and diminished cellular replication. The antimetabolic nature of methotrexate is most effective against the most rapidly dividing cells, making this drug useful in [[Cancer]] [[Pharmaceutical Drugs\|treatment]], and various autoimmune diseases<ref>Methotrexate. (n.d.). UW Department of Orthopaedics and Sports Medicine - Patient Care. Retrieved March 10, 2011, from http://www.orthop.washington.edu/PatientCare/OurServices/Arthritis/Articles/Methotrexate.aspx </ref>.		[[Methotrexate]], formerly known as amethopterin, is a drug that is used in the competitive inhibition of [[Dihydrofolate reductase]], resulting in decreased synthesis of dTTP and diminished cellular replication. The antimetabolic nature of methotrexate is most effective against the most rapidly dividing cells, making this drug useful in [[Cancer]] [[Pharmaceutical Drugs\|treatment]], and various autoimmune diseases<ref>Methotrexate. (n.d.). UW Department of Orthopaedics and Sports Medicine - Patient Care. Retrieved March 10, 2011, from http://www.orthop.washington.edu/PatientCare/OurServices/Arthritis/Articles/Methotrexate.aspx </ref>.