OBrochtasSandbox: Difference between revisions
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This shows the basic structure of the kinase domain with an <scene name='75/750300/Kinase_n_and_c_lobes/1'>N and C lobe</scene>. The ATP will sit between them just below Beta 1 | This shows the basic structure of the kinase domain with an <scene name='75/750300/Kinase_n_and_c_lobes/1'>N and C lobe</scene>. The ATP will sit between them just below Beta 1 | ||
<scene name='75/750300/Inr_atp-cat_loop/1'>This</scene> shows the ATP binding site (purple) and the catalytic loop (green) | <scene name='75/750300/Inr_atp-cat_loop/1'>This</scene> shows the ATP binding site (purple) and the catalytic loop (green). | ||
Here it is as a <scene name='75/750300/Inr_atp-cat_loopspacefill/1'>spacefilled model</scene>. | |||
These are three ts mutations found in other RTKs | |||
G1000S | |||
A1133G | |||
T1221I | |||
Revision as of 20:37, 15 January 2017
==O'Brochta's Sandbox == 0 <StructureSection load='Model.itasser.relax.pdb' size='400' side='right' caption='Anopheles arabiensis InR kinase domain model' scene=>
The Anopheles arabiensis Insulin Receptor's kinase domain was modeled by Brian Pierce for the 'An arab ts lethal project'
This shows the basic structure of the kinase domain with an N and C lobe. The ATP will sit between them just below Beta 1
This shows the ATP binding site (purple) and the catalytic loop (green). Here it is as a spacefilled model.
These are three ts mutations found in other RTKs
G1000S A1133G T1221I
