5mes: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5mes is ~~ON HOLD~~

==MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 29==

~~Authors~~: ~~Hargreaves~~, D.

== Structural highlights ==

<table><tr><td colspan='2'>[[5mes]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MES OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MES FirstGlance].

~~Description: MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 29~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=7LT:(5~{R},13~{S},17~{S})-5-[[4-CHLORANYL-3-(2-PHENYLETHYL)PHENYL]METHYL]-13-[(4-CHLOROPHENYL)METHYL]-8-METHYL-1,4,8,12,16-PENTAZATRICYCLO[15.8.1.0^{20,25}]HEXACOSA-20(25),21,23-TRIENE-3,7,15,26-TETRONE'>7LT</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5mev|5mev]], [[5ku9|5ku9]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mes FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mes OCA], [http://pdbe.org/5mes PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mes RCSB], [http://www.ebi.ac.uk/pdbsum/5mes PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mes ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/MCL1_MOUSE MCL1_MOUSE]] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis.

__TOC__

</StructureSection>

[[Category: Hargreaves, D]]

[[Category: Fab]]

[[Category: Immune system]]

[[Category: Macrocycle]]

[[Category: Mcl1]]

[[Category: Mcl1-fab_55_c6hi]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5mes is ON HOLD
+==MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 29==
+<StructureSection load='5mes' size='340' side='right' caption='[[5mes]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
-Authors: Hargreaves, D.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5mes]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MES OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MES FirstGlance]. <br>
-Description: MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 29
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7LT:(5~{R},13~{S},17~{S})-5-[[4-CHLORANYL-3-(2-PHENYLETHYL)PHENYL]METHYL]-13-[(4-CHLOROPHENYL)METHYL]-8-METHYL-1,4,8,12,16-PENTAZATRICYCLO[15.8.1.0^{20,25}]HEXACOSA-20(25),21,23-TRIENE-3,7,15,26-TETRONE'>7LT</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5mev|5mev]], [[5ku9|5ku9]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mes FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mes OCA], [http://pdbe.org/5mes PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mes RCSB], [http://www.ebi.ac.uk/pdbsum/5mes PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mes ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/MCL1_MOUSE MCL1_MOUSE]] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis.
+__TOC__
+</StructureSection>
 [[Category: Hargreaves, D]]
+[[Category: Fab]]
+[[Category: Immune system]]
+[[Category: Macrocycle]]
+[[Category: Mcl1]]
+[[Category: Mcl1-fab_55_c6hi]]