1rt9: Difference between revisions

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|PDB= 1rt9 |SIZE=350|CAPTION= <scene name='initialview01'>1rt9</scene>, resolution 2.3&Aring;
|PDB= 1rt9 |SIZE=350|CAPTION= <scene name='initialview01'>1rt9</scene>, resolution 2.3&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=IMH:1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL'>IMH</scene>
|LIGAND= <scene name='pdbligand=IMH:1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL'>IMH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span>
|GENE= NP, PNP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= NP, PNP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[1rr6|1RR6]], [[1rsz|1RSZ]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rt9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rt9 OCA], [http://www.ebi.ac.uk/pdbsum/1rt9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rt9 RCSB]</span>
}}
}}


'''Structure of human purine nucleoside phosphorylase in complex with Immucillin-H and sulfate'''
'''Structure of human purine nucleoside phosphorylase in complex with Immucillin-H and sulfate'''


==Disease==
Known diseases associated with this structure: Neutral lipid storage disease with myopathy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=609059 609059]], Nucleoside phosphorylase deficiency, immunodeficiency due to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164050 164050]]


==About this Structure==
==About this Structure==
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[[Category: Shi, W.]]
[[Category: Shi, W.]]
[[Category: Tyler, P C.]]
[[Category: Tyler, P C.]]
[[Category: IMH]]
[[Category: SO4]]
[[Category: pnp]]
[[Category: pnp]]
[[Category: transition state analogue]]
[[Category: transition state analogue]]


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