5hkf: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5hkf is ~~ON HOLD until Paper Publication~~

==Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with 5-phospho-alpha-D-ribosyl 1-diphosphate (PRPP)==

~~Authors~~: ~~Donini~~, S., ~~Ferraris, D~~.M., ~~Bolognesi~~, G., ~~Rizzi~~, M.

== Structural highlights ==

<table><tr><td colspan='2'>[[5hkf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HKF OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HKF FirstGlance].

~~Description~~: ~~Crystal structure~~ of ~~Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with~~ 5-~~phospho-alpha-D-ribosyl~~ 1-diphosphate (~~PRPP~~)

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hkf OCA], [http://pdbe.org/5hkf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hkf RCSB], [http://www.ebi.ac.uk/pdbsum/5hkf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hkf ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/PYRE_MYCTU PYRE_MYCTU]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).

__TOC__

</StructureSection>

[[Category: Orotate phosphoribosyltransferase]]

[[Category: Bolognesi, G]]

[[Category: Donini, S]]

[[Category: Ferraris, D.M]]

[[Category: Ferraris, D M]]

[[Category: Rizzi, M]]

[[Category: De novo pyrimidine nucleotide synthesis]]

[[Category: Oprt]]

[[Category: Prpp complex]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5hkf is ON HOLD  until Paper Publication
+==Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with 5-phospho-alpha-D-ribosyl 1-diphosphate (PRPP)==
+<StructureSection load='5hkf' size='340' side='right' caption='[[5hkf]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
-Authors: Donini, S., Ferraris, D.M., Bolognesi, G., Rizzi, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5hkf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HKF FirstGlance]. <br>
-Description: Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with 5-phospho-alpha-D-ribosyl 1-diphosphate (PRPP)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hkf OCA], [http://pdbe.org/5hkf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hkf RCSB], [http://www.ebi.ac.uk/pdbsum/5hkf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hkf ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/PYRE_MYCTU PYRE_MYCTU]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
+__TOC__
+</StructureSection>
+[[Category: Orotate phosphoribosyltransferase]]
 [[Category: Bolognesi, G]]
 [[Category: Donini, S]]
-[[Category: Ferraris, D.M]]
+[[Category: Ferraris, D M]]
 [[Category: Rizzi, M]]
+[[Category: De novo pyrimidine nucleotide synthesis]]
+[[Category: Oprt]]
+[[Category: Prpp complex]]
+[[Category: Transferase]]