5i5b: Difference between revisions

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'''Unreleased structure'''


The entry 5i5b is ON HOLD until Paper Publication
==quasi racemic structure of allo-Thr13-ShK and D-ShK==
 
<StructureSection load='5i5b' size='340' side='right' caption='[[5i5b]], [[Resolution|resolution]] 0.90&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5i5b]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I5B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5I5B FirstGlance]. <br>
Description:  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LI:LITHIUM+ION'>LI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALO:ALLO-THREONINE'>ALO</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DAR:D-ARGININE'>DAR</scene>, <scene name='pdbligand=DAS:D-ASPARTIC+ACID'>DAS</scene>, <scene name='pdbligand=DCY:D-CYSTEINE'>DCY</scene>, <scene name='pdbligand=DGN:D-GLUTAMINE'>DGN</scene>, <scene name='pdbligand=DHI:D-HISTIDINE'>DHI</scene>, <scene name='pdbligand=DIL:D-ISOLEUCINE'>DIL</scene>, <scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DLY:D-LYSINE'>DLY</scene>, <scene name='pdbligand=DPN:D-PHENYLALANINE'>DPN</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=DSN:D-SERINE'>DSN</scene>, <scene name='pdbligand=DTH:D-THREONINE'>DTH</scene>, <scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene>, <scene name='pdbligand=MED:D-METHIONINE'>MED</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5i5a|5i5a]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5i5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i5b OCA], [http://pdbe.org/5i5b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i5b RCSB], [http://www.ebi.ac.uk/pdbsum/5i5b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5i5b ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/K1A_STIHL K1A_STIHL]] Inhibits voltage-dependent potassium channels. Inhibits Kv1.3/KCNA3 potently and also blocks Kv1.1/KCNA1, Kv1.4/KCNA4, and Kv1.6/KCNA6 at subnanomolar concentrations.<ref>PMID:7660365</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bezanilla, F]]
[[Category: Dang, B]]
[[Category: Kent, S B.H]]
[[Category: Kubota, T]]
[[Category: Mandal, K]]
[[Category: Roux, B]]
[[Category: Shen, R]]
[[Category: Allo-thr13-shk]]
[[Category: D-shk]]
[[Category: Quasi racemic structure]]
[[Category: Toxin]]
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