Sandbox Reserved 1061: Difference between revisions
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{{Sandbox_Reserved_Butler_CH462_Sp2015_#}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | [[Image:Example.jpg]]{{Sandbox_Reserved_Butler_CH462_Sp2015_#}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
== | ==Human Caspase-6== | ||
<StructureSection load=' | <StructureSection load='4FXO' size='340' side='right' caption='Caption for this structure' scene=''> | ||
This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
== Biological Function == | == Biological Function == | ||
Caspase-6 is a protease involved in '''apoptosis'''. It is most notably involved in neurodegenerative diseases, such as Alzheimer's disease and dementia. | |||
== Structural Overview == | |||
== | === Inactive State === | ||
When the protein is in the inactive state it is a '''Homotetramer'''. | |||
=== Active State === | |||
Caspase-6 enters | |||
== Mechanism of Action == | == Mechanism of Action == | ||