2c2z: Difference between revisions

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==~~CRYSTAL STRUCTURE OF CASPASE~~-8 ~~IN COMPLEX WITH AZA~~-~~PEPTIDE MICHAEL ACCEPTOR INHIBITOR~~==

==Crystal structure of caspase-8 in complex with aza-peptide Michael acceptor inhibitor==

== Structural highlights ==

<table><tr><td colspan='2'>[[2c2z]] is a 3 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Human Human]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C2Z OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C2Z FirstGlance].

<table><tr><td colspan='2'>[[2c2z]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C2Z OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C2Z FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene></td></tr>

<tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=MX5:{1-[4-(3,4-DIHYDROQUINOLIN-1(2H)-YL)-4-OXOBUTANOYL]HYDRAZINO}ACETIC+ACID'>MX5</scene>, <scene name='pdbligand=PHQ:BENZYL+CHLOROCARBONATE'>PHQ</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c2z OCA], [http://pdbe.org/2c2z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c2z RCSB], [http://www.ebi.ac.uk/pdbsum/2c2z PDBsum]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c2z OCA], [http://pdbe.org/2c2z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c2z RCSB], [http://www.ebi.ac.uk/pdbsum/2c2z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2c2z ProSAT]</td></tr>

</table>

== Evolutionary Conservation ==

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__TOC__

</StructureSection>

~~[[Category: Human]]~~

[[Category: Asgian, J L]]

[[Category: Campbell, A J]]

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-==CRYSTAL STRUCTURE OF CASPASE-8 IN COMPLEX WITH AZA-PEPTIDE MICHAEL ACCEPTOR INHIBITOR==
+==Crystal structure of caspase-8 in complex with aza-peptide Michael acceptor inhibitor==
 <StructureSection load='2c2z' size='340' side='right' caption='[[2c2z]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2c2z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C2Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C2Z FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2c2z]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C2Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C2Z FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTD:DITHIANE+DIOL'>DTD</scene></td></tr>
 <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MX5:{1-[4-(3,4-DIHYDROQUINOLIN-1(2H)-YL)-4-OXOBUTANOYL]HYDRAZINO}ACETIC+ACID'>MX5</scene>, <scene name='pdbligand=PHQ:BENZYL+CHLOROCARBONATE'>PHQ</scene></td></tr>
 <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1f9e|1f9e]], [[1i4e|1i4e]], [[1qdu|1qdu]], [[1qtn|1qtn]], [[2fun|2fun]]</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c2z OCA], [http://pdbe.org/2c2z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c2z RCSB], [http://www.ebi.ac.uk/pdbsum/2c2z PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c2z OCA], [http://pdbe.org/2c2z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c2z RCSB], [http://www.ebi.ac.uk/pdbsum/2c2z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2c2z ProSAT]</span></td></tr>
 </table>
 == Evolutionary Conservation ==
@@ Line 35: / Line 36: @@
 __TOC__
 </StructureSection>
-[[Category: Human]]
 [[Category: Asgian, J L]]
 [[Category: Campbell, A J]]