5g22: Difference between revisions

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'''Unreleased structure'''


The entry 5g22 is ON HOLD  until Paper Publication
==Plasmodium vivax N-myristoyltransferase in complex with a quinoline inhibitor (compound 26)==
 
<StructureSection load='5g22' size='340' side='right' caption='[[5g22]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
Authors: Goncalves, V., Brannigan, J.A., Laporte, A., Bell, A.S., Roberts, S.M., Wilkinson, A.J., Leatherbarrow, R.J., Tate, E.W.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5g22]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G22 FirstGlance]. <br>
Description: Plasmodium vivax N-myristoyltransferase in complex with a quinoline inhibitor (compound 26)
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NHW:2-OXOPENTADECYL-COA'>NHW</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YN4:ETHYL+4-[(2-CYANOETHYL)SULFANYL]-6-{[6-(PIPERAZIN-1-YL)'>YN4</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5g1z|5g1z]], [[5g20|5g20]], [[5g21|5g21]]</td></tr>
[[Category: Wilkinson, A.J]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr>
[[Category: Leatherbarrow, R.J]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5g22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g22 OCA], [http://pdbe.org/5g22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g22 RCSB], [http://www.ebi.ac.uk/pdbsum/5g22 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g22 ProSAT]</span></td></tr>
[[Category: Brannigan, J.A]]
</table>
== Function ==
[[http://www.uniprot.org/uniprot/A5K1A2_PLAVS A5K1A2_PLAVS]] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (By similarity).[RuleBase:RU000586]  
__TOC__
</StructureSection>
[[Category: Glycylpeptide N-tetradecanoyltransferase]]
[[Category: Bell, A S]]
[[Category: Brannigan, J A]]
[[Category: Goncalves, V]]
[[Category: Goncalves, V]]
[[Category: Roberts, S.M]]
[[Category: Tate, E.W]]
[[Category: Laporte, A]]
[[Category: Laporte, A]]
[[Category: Bell, A.S]]
[[Category: Leatherbarrow, R J]]
[[Category: Roberts, S M]]
[[Category: Tate, E W]]
[[Category: Wilkinson, A J]]
[[Category: Drug design]]
[[Category: Inhibitor]]
[[Category: Malaria]]
[[Category: Myristoylation]]
[[Category: Quinoline]]
[[Category: Transferase]]
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