5ith: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5ith is ~~ON HOLD until Mar 16 2018~~

==TIA-1 RRM2 recognition of target oligonucleotide==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5ith]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ITH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ITH FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ith OCA], [http://pdbe.org/5ith PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ith RCSB], [http://www.ebi.ac.uk/pdbsum/5ith PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ith ProSAT]</span></td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.

__TOC__

</StructureSection>

[[Category: Waris, S]]

[[Category: Wilce, J A]]

[[Category: Wilce, M C]]

[[Category: Aromatic base stacking interaction]]

[[Category: Dna binding protein-dna complex]]

[[Category: Poly u binding preference]]

[[Category: Rna binding protein-dna complex]]

[[Category: Rna/dna binding domain]]

[[Category: Rrm]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5ith is ON HOLD  until Mar 16 2018
+==TIA-1 RRM2 recognition of target oligonucleotide==
+<StructureSection load='5ith' size='340' side='right' caption='[[5ith]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5ith]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ITH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ITH FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ith FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ith OCA], [http://pdbe.org/5ith PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ith RCSB], [http://www.ebi.ac.uk/pdbsum/5ith PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ith ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
+__TOC__
+</StructureSection>
+[[Category: Waris, S]]
+[[Category: Wilce, J A]]
+[[Category: Wilce, M C]]
+[[Category: Aromatic base stacking interaction]]
+[[Category: Dna binding protein-dna complex]]
+[[Category: Poly u binding preference]]
+[[Category: Rna binding protein-dna complex]]
+[[Category: Rna/dna binding domain]]
+[[Category: Rrm]]