5itw: Difference between revisions
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==Crystal structure of Bacillus subtilis BacC Dihydroanticapsin 7-dehydrogenase== | |||
<StructureSection load='5itw' size='340' side='right' caption='[[5itw]], [[Resolution|resolution]] 1.19Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5itw]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ITW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ITW FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5itv|5itv]]</td></tr> | ||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroanticapsin_7-dehydrogenase Dihydroanticapsin 7-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.385 1.1.1.385] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5itw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5itw OCA], [http://pdbe.org/5itw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5itw RCSB], [http://www.ebi.ac.uk/pdbsum/5itw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5itw ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/BACC_BACSU BACC_BACSU]] Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the dehydrogenation of the C7-hydroxyl group in the 4S-tetrahydrotyrosine (4S-H4Tyr) to yield anticapsin (epoxycyclohexanonyl-Ala). It is not able to oxidize the 4R-H4Tyr diastereomer and the dihydrobacilysin dipeptide (L-Ala-4S-H4Tyr dipeptide).<ref>PMID:15609023</ref> <ref>PMID:23317005</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Dihydroanticapsin 7-dehydrogenase]] | |||
[[Category: Balaram, H]] | [[Category: Balaram, H]] | ||
[[Category: Gopal, B]] | [[Category: Gopal, B]] | ||
[[Category: Row, T | [[Category: Perinbam, K]] | ||
[[Category: Row, T N.G]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Rossmann fold]] | |||
[[Category: Short-chain dehydrogenases/reductase]] | |||
Revision as of 01:36, 11 March 2017
Crystal structure of Bacillus subtilis BacC Dihydroanticapsin 7-dehydrogenase
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