5t4m: Difference between revisions
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The entry | ==Crystal Structure of Human Protocadherin-15 EC3-5== | ||
<StructureSection load='5t4m' size='340' side='right' caption='[[5t4m]], [[Resolution|resolution]] 2.24Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5t4m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T4M FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5t4n|5t4n]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t4m OCA], [http://pdbe.org/5t4m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t4m RCSB], [http://www.ebi.ac.uk/pdbsum/5t4m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t4m ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/PCD15_HUMAN PCD15_HUMAN]] Usher syndrome type 1;Autosomal recessive non-syndromic sensorineural deafness type DFNB. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting distinct genetic loci, including the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PCD15_HUMAN PCD15_HUMAN]] Calcium-dependent cell-adhesion protein. Essential for maintenance of normal retinal and cochlear function. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Gaudet, R]] | |||
[[Category: Powers, R E]] | |||
[[Category: Sotomayor, M]] | |||
[[Category: Cadherin]] | |||
[[Category: Cell adhesion]] | |||
[[Category: Hearing]] | |||
[[Category: Mechanotransduction]] | |||
Revision as of 01:41, 11 March 2017
Crystal Structure of Human Protocadherin-15 EC3-5
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