1tg2: Difference between revisions

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|PDB= 1tg2 |SIZE=350|CAPTION= <scene name='initialview01'>1tg2</scene>, resolution 2.20&Aring;
|PDB= 1tg2 |SIZE=350|CAPTION= <scene name='initialview01'>1tg2</scene>, resolution 2.20&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene> and <scene name='pdbligand=H2B:2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE'>H2B</scene>
|LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=H2B:2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE'>H2B</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span>
|GENE= PAH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= PAH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[1pah|1PAH]], [[1tdw|1TDW]], [[1lrm|1LRM]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tg2 OCA], [http://www.ebi.ac.uk/pdbsum/1tg2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1tg2 RCSB]</span>
}}
}}


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==Disease==
==Disease==
Known diseases associated with this structure: Hyperphenylalaninemia, mild OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=261600 261600]], Phenylketonuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=261600 261600]]
Known disease associated with this structure: Phenylketonuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=261600 261600]], Hyperphenylalaninemia, mild OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=261600 261600]]


==About this Structure==
==About this Structure==
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[[Category: Tyring, S.]]
[[Category: Tyring, S.]]
[[Category: Ugarte, M.]]
[[Category: Ugarte, M.]]
[[Category: FE]]
[[Category: phenylalanine hydroxylase phenylketonuria mutant a313t in complex with cofactor analogue 7,8-dihydrobiopterin]]
[[Category: H2B]]
[[Category: 8-dihydrobiopterin]]
[[Category: phenylalanine hydroxylase phenylketonuria mutant a313t in complex with cofactor analogue 7]]


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