Sandbox Reserved 1061: Difference between revisions
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== Biological Function == | == Biological Function == | ||
Caspase-6 is a protease involved in '''apoptosis'''. It is most notably involved in neurodegenerative diseases, such as Alzheimer's disease and dementia. | Caspase-6 is a member of the Cysteine-Aspartic protease family, and involved in '''apoptosis'''. It is most notably involved in neurodegenerative diseases, such as Alzheimer's disease and dementia. | ||
== Structural Overview == | == Structural Overview == | ||
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== Mechanism of Action == | == Mechanism of Action == | ||
Mechanism is unknown as of right now. The active sight is known to be HIS-121, CYS-163, and GLU-174. | Mechanism is unknown as of right now. The active sight is known to be HIS-121, CYS-163, and GLU-174. It is tightly regulated by Zinc binding to an allosteric site. | ||
== Zinc Ligand(s) == | == Zinc Ligand(s) == | ||
The Zinc ligand is known to inhibit the | |||
== Other Ligands == | == Other Ligands == | ||
Other ligands that bind to Caspase-6 are caspase-8, which is activated within the caspase-chain by Caspase 6. | |||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | |||
