Sandbox Reserved 1061: Difference between revisions
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Text To Be Displayed</scene>[[Image:Caspase_6.jpg|100 px|left|thumb|Figure Legend]]{{Sandbox_Reserved_Butler_CH462_Sp2015_#}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | <scene name='69/694228/Activated_protein/1'> Activated Caspase-6 </scene>Text To Be Displayed</scene>[[Image:Caspase_6.jpg|100 px|left|thumb|Figure Legend]]{{Sandbox_Reserved_Butler_CH462_Sp2015_#}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
==Human Caspase-6== | ==Human Caspase-6== | ||
<StructureSection load='4FXO' size='340' side='right' caption='Caspase-6' scene=''> <scene name='69/694228/Caspase_6_dot_representation/1'>Caspase-6 dot representation</scene> | <StructureSection load='4FXO' size='340' side='right' caption='Caspase-6' scene=''> <scene name='69/694228/Caspase_6_dot_representation/1'>Caspase-6 dot representation</scene> | ||
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=== Active State === | === Active State === | ||
Caspase-6 enters the active state by self-cleaving at residue 193 after a sequence of '''TEVD'''. The protein then becomes a Tetramer of Dimers. | Caspase-6 enters the active state by self-cleaving at residue 193 after a sequence of '''TEVD'''. The protein then becomes a Tetramer of Dimers. | ||
<scene name='69/694228/Activated_protein/1'> Activated Caspase-6 </scene>Text To Be Displayed</scene>[[Image:Caspase_6.jpg|100 px|left|thumb|Figure Legend]] | |||
== Mechanism of Action == | == Mechanism of Action == | ||
Mechanism is unknown as of right now. The active sight is known to be HIS-121, CYS-163, and GLU-174. It is tightly regulated by Zinc binding to an allosteric site. | Mechanism is unknown as of right now. The active sight is known to be HIS-121, CYS-163, and GLU-174. It is tightly regulated by Zinc binding to an allosteric site. | ||
