Sandbox1996: Difference between revisions

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== Function ==

Chlorothiazide promotes water loss in the body and inhibits the Na+/Cl- reabsorption from the distal convoluted tubules in the kidney. It also inhibits sodium ion transport across the renal tubular epithelium by binding to the thiazide sensitive sodium-chloride transporter. This results in elimination of potassium removal by the sodium-potassium exchange mechanism. Chlorothiazide acts as an inhibitor and has several targets and functions in the human body. Chlorothiazide that target solute carrier family 12 member 3 function is to mediate sodium and chloride reabsorption in the nephron segment to have ample renal sodium reabsorption. Chlorothiazide that targets carbonic anhydrase 1 functions to do the reversible hydration of carbon dioxide. Chlorothiazide that targets carbonic anhydrase 2 functions to the reversible hydration of carbon dioxide, as well as regulate the fluid secretion of the anterior chamber of the eye, regulate intracellular pH in the duodenal upper villous epithelium durin proton-coupled peptide absorption, and stimulate the chloride-bicarbonate exchange activity of SLC26A6. Chlorothiazide that targets carbonic anhydrase 4 also function to do the reversible hydration of carbon dioxide and also stimulates the sodium/bicarbonate transporter activity of SLC4A4, and is vital for acid overload removal from the retina and retina epithelium (3).

Chlorothiazide promotes water loss in the body and inhibits the Na+/Cl- reabsorption from the distal convoluted tubules in the kidney. It also inhibits sodium ion transport across the renal tubular epithelium by binding to the thiazide sensitive sodium-chloride transporter. This results in elimination of potassium removal by the sodium-potassium exchange mechanism. Chlorothiazide acts as an inhibitor and has several targets and functions in the human body. Chlorothiazide that target solute carrier family 12 member 3 function is to mediate sodium and chloride reabsorption in the nephron segment to have ample renal sodium reabsorption. Chlorothiazide that targets <scene name='75/756546/Carbonic_anhydrase_1/1'>carbonic anhydrase 1</scene> functions to do the reversible hydration of carbon dioxide. Chlorothiazide that targets <scene name='75/756546/Carbonic_anhydrase_2/1'>carbonic anhydrase 2</scene> functions to the reversible hydration of carbon dioxide, as well as regulate the fluid secretion of the anterior chamber of the eye, regulate intracellular pH in the duodenal upper villous epithelium durin proton-coupled peptide absorption, and stimulate the chloride-bicarbonate exchange activity of SLC26A6. Chlorothiazide that targets <scene name='75/756546/Carbonic_anhydrase_4/1'>carbonic anhydrase 4</scene> also function to do the reversible hydration of carbon dioxide and also stimulates the sodium/bicarbonate transporter activity of SLC4A4, and is vital for acid overload removal from the retina and retina epithelium (3).

== Structure ==

Sandbox1996: Difference between revisions

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 == Function ==
-Chlorothiazide promotes water loss in the body and inhibits the Na+/Cl- reabsorption from the distal convoluted tubules in the kidney. It also inhibits sodium ion transport across the renal tubular epithelium by binding to the thiazide sensitive sodium-chloride transporter. This results in elimination of potassium removal by the sodium-potassium exchange mechanism. Chlorothiazide acts as an inhibitor and has several targets and functions in the human body. Chlorothiazide that target solute carrier family 12 member 3 function is to mediate sodium and chloride reabsorption in the nephron segment to have ample renal sodium reabsorption. Chlorothiazide that targets carbonic anhydrase 1 functions to do the reversible hydration of carbon dioxide. Chlorothiazide that targets carbonic anhydrase 2 functions to the reversible hydration of carbon dioxide, as well as regulate the fluid secretion of the anterior chamber of the eye, regulate intracellular pH in the duodenal upper villous epithelium durin proton-coupled peptide absorption, and stimulate the chloride-bicarbonate exchange activity of SLC26A6. Chlorothiazide that targets carbonic anhydrase 4 also function to do the reversible hydration of carbon dioxide and also stimulates the sodium/bicarbonate transporter activity of SLC4A4, and is vital for acid overload removal from the retina and retina epithelium (3).
+Chlorothiazide promotes water loss in the body and inhibits the Na+/Cl- reabsorption from the distal convoluted tubules in the kidney. It also inhibits sodium ion transport across the renal tubular epithelium by binding to the thiazide sensitive sodium-chloride transporter. This results in elimination of potassium removal by the sodium-potassium exchange mechanism. Chlorothiazide acts as an inhibitor and has several targets and functions in the human body. Chlorothiazide that target solute carrier family 12 member 3 function is to mediate sodium and chloride reabsorption in the nephron segment to have ample renal sodium reabsorption. Chlorothiazide that targets <scene name='75/756546/Carbonic_anhydrase_1/1'>carbonic anhydrase 1</scene> functions to do the reversible hydration of carbon dioxide. Chlorothiazide that targets <scene name='75/756546/Carbonic_anhydrase_2/1'>carbonic anhydrase 2</scene> functions to the reversible hydration of carbon dioxide, as well as regulate the fluid secretion of the anterior chamber of the eye, regulate intracellular pH in the duodenal upper villous epithelium durin proton-coupled peptide absorption, and stimulate the chloride-bicarbonate exchange activity of SLC26A6. Chlorothiazide that targets <scene name='75/756546/Carbonic_anhydrase_4/1'>carbonic anhydrase 4</scene> also function to do the reversible hydration of carbon dioxide and also stimulates the sodium/bicarbonate transporter activity of SLC4A4, and is vital for acid overload removal from the retina and retina epithelium (3).
 == Structure ==