5in2: Difference between revisions
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==Crystal structure of extra cellular Cu/Zn Superoxide Dismutase from Onchocerca volvulus at 1.5 Angstrom; Insight into novel binding site and new inhibitors== | |||
<StructureSection load='5in2' size='340' side='right' caption='[[5in2]], [[Resolution|resolution]] 1.55Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5in2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IN2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IN2 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5in2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5in2 OCA], [http://pdbe.org/5in2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5in2 RCSB], [http://www.ebi.ac.uk/pdbsum/5in2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5in2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/SODE_ONCVO SODE_ONCVO]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May act in the parasite defense against phagocyte-generated reactive oxygen species. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Superoxide dismutase]] | |||
[[Category: Betzel, C]] | [[Category: Betzel, C]] | ||
[[Category: Moustafa, A]] | [[Category: Moustafa, A]] | ||
[[Category: Perbandt, M]] | [[Category: Perbandt, M]] | ||
[[Category: Ec ov-sod]] | |||
[[Category: Onchcerca volvulus]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Prodrug]] | |||
Revision as of 13:43, 29 March 2017
Crystal structure of extra cellular Cu/Zn Superoxide Dismutase from Onchocerca volvulus at 1.5 Angstrom; Insight into novel binding site and new inhibitors
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