5t4j: Difference between revisions
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==PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation== | |||
<StructureSection load='5t4j' size='340' side='right' caption='[[5t4j]], [[Resolution|resolution]] 2.23Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5t4j]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T4J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T4J FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABU:GAMMA-AMINO-BUTANOIC+ACID'>ABU</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t4j OCA], [http://pdbe.org/5t4j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t4j RCSB], [http://www.ebi.ac.uk/pdbsum/5t4j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t4j ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/GABR_BACSU GABR_BACSU]] Activates the transcription of the gabTD operon. Is also a repressor of its own expression, both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma-aminobutyrate.<ref>PMID:12123465</ref> <ref>PMID:15223311</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Belitsky, B R]] | |||
[[Category: Farley, M]] | |||
[[Category: Juncosa, J I]] | |||
[[Category: Le, H V]] | |||
[[Category: Lehrer, H J.S]] | |||
[[Category: Liu, D]] | [[Category: Liu, D]] | ||
[[Category: | [[Category: Petsko, G A]] | ||
[[Category: Ringe, D]] | [[Category: Ringe, D]] | ||
[[Category: Sanishvili, R]] | |||
[[Category: Silverman, R B]] | |||
[[Category: Wu, R]] | [[Category: Wu, R]] | ||
[[Category: | [[Category: External aldimine]] | ||
[[Category: | [[Category: Gaba]] | ||
[[Category: | [[Category: Gabr]] | ||
[[Category: | [[Category: Mocr]] | ||
[[Category: | [[Category: Plp]] | ||
[[Category: Transcription regulator]] | |||
Revision as of 14:04, 29 March 2017
PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation
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