Sandbox Reserved 1070: Difference between revisions
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===CZB Domain=== | ===CZB Domain=== | ||
The CZB domain is responsible for regulating the function of DgcZ. Four residues bind zinc with a high affinity even at 10<sup>-16M</sup> concentrations. | The CZB domain is responsible for regulating the function of DgcZ. Four residues bind zinc with a high affinity even at 10<sup>-16M</sup> concentrations. | ||
== Mechanism of Action == | == Mechanism of Action == | ||
Diguanylate cyclases only function efficiently as dimers, to bind both GGDEF domains holding the substrates. The presence of Zinc disrupts the ability of the two domains to overlap. | Diguanylate cyclases only function efficiently as dimers, to bind both GGDEF domains holding the substrates. The presence of Zinc disrupts the ability of the two domains to overlap. | ||
