5j13: Difference between revisions
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==Cytokine antibody complex== | |||
<StructureSection load='5j13' size='340' side='right' caption='[[5j13]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5j13]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J13 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J13 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j13 OCA], [http://pdbe.org/5j13 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j13 RCSB], [http://www.ebi.ac.uk/pdbsum/5j13 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j13 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/TSLP_HUMAN TSLP_HUMAN]] Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.<ref>PMID:11418668</ref> <ref>PMID:11480573</ref> <ref>PMID:17242164</ref> Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin.<ref>PMID:24850429</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Savvides, S N]] | |||
[[Category: Verstraete, K]] | |||
[[Category: Cytokine inflammation tslp antibody]] | |||
[[Category: Immune system]] | |||
