5hj2: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5hj2 is ~~ON HOLD until Paper Publication~~

==Integrin alpha2beta1 I-domain==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5hj2]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HJ2 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HJ2 FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5hgj|5hgj]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hj2 OCA], [http://pdbe.org/5hj2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hj2 RCSB], [http://www.ebi.ac.uk/pdbsum/5hj2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hj2 ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/ITA2_HUMAN ITA2_HUMAN]] Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.

__TOC__

</StructureSection>

[[Category: Banerjee, S]]

[[Category: Brown, K L]]

[[Category: Adhesion]]

[[Category: Cell adhesion]]

[[Category: Signaling]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5hj2 is ON HOLD  until Paper Publication
+==Integrin alpha2beta1 I-domain==
+<StructureSection load='5hj2' size='340' side='right' caption='[[5hj2]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5hj2]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HJ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HJ2 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hgj|5hgj]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hj2 OCA], [http://pdbe.org/5hj2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hj2 RCSB], [http://www.ebi.ac.uk/pdbsum/5hj2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hj2 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/ITA2_HUMAN ITA2_HUMAN]] Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
+__TOC__
+</StructureSection>
+[[Category: Banerjee, S]]
+[[Category: Brown, K L]]
+[[Category: Adhesion]]
+[[Category: Cell adhesion]]
+[[Category: Signaling]]