Sandbox Reserved 1072: Difference between revisions

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 ==Other Ligands==
-c-di-GMP and GTP bind <scene name='69/694239/Flldgczwithc-di_and_allosteric/3'>allosterically</scene> although the function of this binding is unknown. Very weak product inhibition was observed when c-di-GMP bound allosterically but the inhibition was so weak, it is possible the c-di-GMP actually interacts with another as of yet unknown molecule at that site<sup>[9]</sup>.
+Additional c-di-GMP and GTP molecules bind <scene name='69/694239/Flldgczwithc-di_and_allosteric/3'>allosterically</scene> to inhibitory sites on the exterior of the GGEEF domains, preventing the half sites from forming the active site and causing a reaction. The complete function of this binding is not yet well characterized. Weak product inhibition was observed when c-di-GMP bound allosterically, but the inhibition was so weak, it is possible that the c-di-GMP actually interacts with another unknown molecule at that site<sup>[9]</sup>.
 ==See Also==

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