5k4m: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5k4m is ~~ON HOLD until Paper Publication~~

==Directed evolutionary changes in MBL super family - NDM-1 Round 10 crystal-3==

~~Authors~~: ~~Hong~~, N.-S., ~~Jackson~~, C.J., ~~Carr~~, P.D.

== Structural highlights ==

<table><tr><td colspan='2'>[[5k4m]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K4M OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K4M FirstGlance].

~~Description~~: ~~Directed evolutionary changes in MBL super family~~ -~~NDM~~-~~1 Round 10 crystal-3~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NPO:P-NITROPHENOL'>NPO</scene>, <scene name='pdbligand=SV7:PHENYLPHOSPHONIC+ACID'>SV7</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5jqj|5jqj]], [[5k4k|5k4k]], [[5k4n|5k4n]]</td></tr>

[[Category: Hong, N.-S]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </td></tr>

[[Category: Jackson, C.J]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k4m OCA], [http://pdbe.org/5k4m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k4m RCSB], [http://www.ebi.ac.uk/pdbsum/5k4m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k4m ProSAT]</td></tr>

[[Category: ~~Carr, P.D~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN]] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.

__TOC__

</StructureSection>

[[Category: Beta-lactamase]]

[[Category: Carr, P D]]

[[Category: Hong, N S]]

[[Category: Jackson, C J]]

[[Category: Directed evolution]]

[[Category: Hydrolase]]

[[Category: Mbl super family]]

[[Category: Ndm-1]]

[[Category: Phosphatase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5k4m is ON HOLD  until Paper Publication
+==Directed evolutionary changes in MBL super family - NDM-1 Round 10 crystal-3==
+<StructureSection load='5k4m' size='340' side='right' caption='[[5k4m]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
-Authors: Hong, N.-S., Jackson, C.J., Carr, P.D.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5k4m]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K4M FirstGlance]. <br>
-Description: Directed evolutionary changes in MBL super family -NDM-1 Round 10 crystal-3
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NPO:P-NITROPHENOL'>NPO</scene>, <scene name='pdbligand=SV7:PHENYLPHOSPHONIC+ACID'>SV7</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jqj|5jqj]], [[5k4k|5k4k]], [[5k4n|5k4n]]</td></tr>
-[[Category: Hong, N.-S]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-[[Category: Jackson, C.J]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k4m OCA], [http://pdbe.org/5k4m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k4m RCSB], [http://www.ebi.ac.uk/pdbsum/5k4m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k4m ProSAT]</span></td></tr>
-[[Category: Carr, P.D]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN]] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
+__TOC__
+</StructureSection>
+[[Category: Beta-lactamase]]
+[[Category: Carr, P D]]
+[[Category: Hong, N S]]
+[[Category: Jackson, C J]]
+[[Category: Directed evolution]]
+[[Category: Hydrolase]]
+[[Category: Mbl super family]]
+[[Category: Ndm-1]]
+[[Category: Phosphatase]]