1uz4: Difference between revisions

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|PDB= 1uz4 |SIZE=350|CAPTION= <scene name='initialview01'>1uz4</scene>, resolution 1.71&Aring;
|PDB= 1uz4 |SIZE=350|CAPTION= <scene name='initialview01'>1uz4</scene>, resolution 1.71&Aring;
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+A'>AC1</scene>
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=IFL:(3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE'>IFL</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IFL:(3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE'>IFL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uz4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uz4 OCA], [http://www.ebi.ac.uk/pdbsum/1uz4 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1uz4 RCSB]</span>
}}
}}


Line 21: Line 24:
[[Category: Davies, G J.]]
[[Category: Davies, G J.]]
[[Category: Vincent, F.]]
[[Category: Vincent, F.]]
[[Category: GOL]]
[[Category: IFL]]
[[Category: SO4]]
[[Category: hydrolase]]
[[Category: hydrolase]]
[[Category: inhibitor]]
[[Category: inhibitor]]
Line 29: Line 29:
[[Category: mannosidase]]
[[Category: mannosidase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:38:53 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:17:24 2008''

Revision as of 21:17, 30 March 2008

File:1uz4.gif


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1uz4, resolution 1.71Å
Sites: AC1
Ligands: GOL, IFL, SO4
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



COMMON INHIBITION OF BETA-GLUCOSIDASE AND BETA-MANNOSIDASE BY ISOFAGOMINE LACTAM REFLECTS DIFFERENT CONFORMATIONAL INTINERARIES FOR GLUCOSIDE AND MANNOSIDE HYDROLYSIS


About this Structure

1UZ4 is a Single protein structure of sequence from Cellvibrio mixtus. Full crystallographic information is available from OCA.

Reference

Common inhibition of both beta-glucosidases and beta-mannosidases by isofagomine lactam reflects different conformational itineraries for pyranoside hydrolysis., Vincent F, Gloster TM, Macdonald J, Morland C, Stick RV, Dias FM, Prates JA, Fontes CM, Gilbert HJ, Davies GJ, Chembiochem. 2004 Nov 5;5(11):1596-9. PMID:15515081

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