5t2h: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 5t2h is ON HOLD until Paper Publication~~

==Engineered variant of I-OnuI meganuclease targeting the Human TCRa gene; harbors 43 point mutations relative to wild-type I-OnuI==

~~Authors: Stoddard, B.L., Werther, R.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5t2h]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T2H OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T2H FirstGlance].

~~Description:~~ Engineered variant of I-OnuI meganuclease targeting the Human TCRa gene; harbors 43 point mutations relative to wild-type I-OnuI

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5t2j|5t2j]], [[5t2n|5t2n]], [[5t2o|5t2o]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t2h OCA], [http://pdbe.org/5t2h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t2h RCSB], [http://www.ebi.ac.uk/pdbsum/5t2h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t2h ProSAT]</td></tr>

</table>

__TOC__

</StructureSection>

[[Category: Stoddard, B L]]

[[Category: Werther, R]]

[[Category: ~~Stoddard, B.L~~]]

[[Category: Dna complex]]

[[Category: Engineered protein]]

[[Category: Homing endonuclease]]

[[Category: Hydrolase-dna complex]]

[[Category: Meganuclease]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5t2h is ON HOLD  until Paper Publication
+==Engineered variant of I-OnuI meganuclease targeting the Human TCRa gene; harbors 43 point mutations relative to wild-type I-OnuI==
+<StructureSection load='5t2h' size='340' side='right' caption='[[5t2h]], [[Resolution|resolution]] 2.52&Aring;' scene=''>
-Authors: Stoddard, B.L., Werther, R.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5t2h]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T2H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T2H FirstGlance]. <br>
-Description: Engineered variant of I-OnuI meganuclease targeting the Human TCRa gene; harbors 43 point mutations relative to wild-type I-OnuI
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5t2j|5t2j]], [[5t2n|5t2n]], [[5t2o|5t2o]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t2h OCA], [http://pdbe.org/5t2h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t2h RCSB], [http://www.ebi.ac.uk/pdbsum/5t2h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t2h ProSAT]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
+[[Category: Stoddard, B L]]
 [[Category: Werther, R]]
-[[Category: Stoddard, B.L]]
+[[Category: Dna complex]]
+[[Category: Engineered protein]]
+[[Category: Homing endonuclease]]
+[[Category: Hydrolase-dna complex]]
+[[Category: Meganuclease]]