5jkk: Difference between revisions
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==Crystal structure of the negatively supercharged variant Ftn(neg) of human heavy chain ferritin== | |||
<StructureSection load='5jkk' size='340' side='right' caption='[[5jkk]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5jkk]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JKK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JKK FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jkk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jkk OCA], [http://pdbe.org/5jkk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jkk RCSB], [http://www.ebi.ac.uk/pdbsum/5jkk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jkk ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Ferroxidase]] | |||
[[Category: Beck, T]] | |||
[[Category: Kuenzle, M]] | |||
[[Category: Binary nanoparticle superlattice]] | |||
[[Category: Binary protein structure]] | |||
[[Category: Charged protein container]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Protein design]] | |||
[[Category: Protein engineering]] | |||
[[Category: Self-assembly]] | |||
Revision as of 12:56, 10 May 2017
Crystal structure of the negatively supercharged variant Ftn(neg) of human heavy chain ferritin
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