5ugh: Difference between revisions
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==Crystal structure of Mat2a bound to the allosteric inhibitor PF-02929366== | |||
<StructureSection load='5ugh' size='340' side='right' caption='[[5ugh]], [[Resolution|resolution]] 2.06Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ugh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UGH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UGH FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8AJ:(E)-2-(7-CHLORO-5-PHENYL[1,2,4]TRIAZOLO[4,3-A]QUINOLIN-1-YL)-N,N-DIMETHYLETHEN-1-AMINE'>8AJ</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_adenosyltransferase Methionine adenosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.6 2.5.1.6] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ugh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ugh OCA], [http://pdbe.org/5ugh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ugh RCSB], [http://www.ebi.ac.uk/pdbsum/5ugh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ugh ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/METK2_HUMAN METK2_HUMAN]] Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Methionine adenosyltransferase]] | |||
[[Category: Feng, J]] | |||
[[Category: Kaiser, S E]] | |||
[[Category: Stewart, A E]] | |||
[[Category: Mat2a]] | |||
[[Category: Sam]] | |||
[[Category: Transferase]] | |||
Revision as of 15:50, 17 May 2017
Crystal structure of Mat2a bound to the allosteric inhibitor PF-02929366
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