5vew: Difference between revisions
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The | ==Structure of the human GLP-1 receptor complex with PF-06372222== | ||
<StructureSection load='5vew' size='340' side='right' caption='[[5vew]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5vew]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VEW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VEW FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=97Y:N-{4-[(R)-(3,3-DIMETHYLCYCLOBUTYL)({6-[4-(TRIFLUOROMETHYL)-1H-IMIDAZOL-1-YL]PYRIDIN-3-YL}AMINO)METHYL]BENZENE-1-CARBONYL}-BETA-ALANINE'>97Y</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr> | |||
[[Category: | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5vex|5vex]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vew OCA], [http://pdbe.org/5vew PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vew RCSB], [http://www.ebi.ac.uk/pdbsum/5vew PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vew ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/GLP1R_HUMAN GLP1R_HUMAN]] This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Lysozyme]] | |||
[[Category: Cai, X]] | |||
[[Category: Dai, A]] | |||
[[Category: Graaf, C D]] | |||
[[Category: Han, G W]] | |||
[[Category: Hanson, M A]] | |||
[[Category: Jiang, S]] | |||
[[Category: Lau, J]] | |||
[[Category: Lin, G]] | |||
[[Category: Liu, D]] | |||
[[Category: Liu, K]] | |||
[[Category: Liu, Z J]] | |||
[[Category: Song, G]] | |||
[[Category: Stevens, R C]] | |||
[[Category: Wang, M W]] | |||
[[Category: Wang, Y]] | |||
[[Category: Wu, B]] | |||
[[Category: Wu, F]] | |||
[[Category: Wu, Y]] | |||
[[Category: Yang, D]] | |||
[[Category: Ye, L]] | |||
[[Category: Zhao, S]] | |||
[[Category: Zhou, Q]] | |||
[[Category: 7tm domain]] | |||
[[Category: Class b]] | |||
[[Category: Gpcr]] | |||
[[Category: Signaling protein]] | |||
[[Category: Treatment of type 2 diabetes]] | |||
Revision as of 13:51, 24 May 2017
Structure of the human GLP-1 receptor complex with PF-06372222
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