Virus protease: Difference between revisions
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{{STRUCTURE_1odw| PDB=1odw | SIZE=350| SCENE=Virus_protease/Cv/1 |right|CAPTION=HIV-1 protease dimer complex with tert-butylcarbonate [[1odw]] }} | |||
'''Virus proteases''' include HIV protease, XMRV protease, retropepsin. | '''Virus proteases''' include HIV protease, XMRV protease, retropepsin. | ||
HIV Protease (HIV-PR) and xenotropic murine leukemia virus protease (XMRV-PR) cleave polyproteins to produce the mature proteins of the virus. Both are aspartyl proteases. The inhibition of HIV-PR results in an uninfectious HIV virion. HIV-1 is found globally while HIV-2, which has lower virulence, is found in West Africa. | HIV Protease (HIV-PR) and xenotropic murine leukemia virus protease (XMRV-PR) cleave polyproteins to produce the mature proteins of the virus. Both are aspartyl proteases. The inhibition of HIV-PR results in an uninfectious HIV virion. HIV-1 is found globally while HIV-2, which has lower virulence, is found in West Africa. | ||
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*[[Molecular Playground/Dengue Virus Protease]] | *[[Molecular Playground/Dengue Virus Protease]] | ||
== 3D Structures of Virus proteases == | == 3D Structures of Virus proteases == | ||
