1dq5: Difference between revisions

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==Manganese;Manganese concanavalin A at pH 5.0==

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</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dq5 OCA], [http://pdbe.org/1dq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dq5 RCSB], [http://www.ebi.ac.uk/pdbsum/1dq5 PDBsum]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dq5 OCA], [http://pdbe.org/1dq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dq5 RCSB], [http://www.ebi.ac.uk/pdbsum/1dq5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1dq5 ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/~~CONA_CANEN CONA_CANEN~~]] D-mannose specific lectin.

[[http://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR]] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

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 ==Manganese;Manganese concanavalin A at pH 5.0==
 <StructureSection load='1dq5' size='340' side='right' caption='[[1dq5]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
@@ Line 5: / Line 6: @@
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
 <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dq0|1dq0]], [[1dq1|1dq1]], [[1dq2|1dq2]], [[1dq4|1dq4]], [[1dq6|1dq6]]</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dq5 OCA], [http://pdbe.org/1dq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dq5 RCSB], [http://www.ebi.ac.uk/pdbsum/1dq5 PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dq5 OCA], [http://pdbe.org/1dq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dq5 RCSB], [http://www.ebi.ac.uk/pdbsum/1dq5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1dq5 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/CONA_CANEN CONA_CANEN]] D-mannose specific lectin.
+[[http://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR]] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]