5nmb: Difference between revisions
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{{Large structure}} | |||
==Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain== | ==Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain== | ||
<StructureSection load='5nmb' size='340' side='right' caption='[[5nmb]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='5nmb' size='340' side='right' caption='[[5nmb]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nmb OCA], [http://pdbe.org/5nmb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nmb RCSB], [http://www.ebi.ac.uk/pdbsum/5nmb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nmb ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nmb OCA], [http://pdbe.org/5nmb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nmb RCSB], [http://www.ebi.ac.uk/pdbsum/5nmb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nmb ProSAT]</span></td></tr> | ||
</table> | </table> | ||
{{Large structure}} | |||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/NCOA1_HUMAN NCOA1_HUMAN]] Note=A chromosomal aberration involving NCOA1 is a cause of rhabdomyosarcoma. Translocation t(2;2)(q35;p23) with PAX3 generates the NCOA1-PAX3 oncogene consisting of the N-terminus part of PAX3 and the C-terminus part of NCOA1. The fusion protein acts as a transcriptional activator. Rhabdomyosarcoma is the most common soft tissue carcinoma in childhood, representing 5-8% of all malignancies in children. | [[http://www.uniprot.org/uniprot/NCOA1_HUMAN NCOA1_HUMAN]] Note=A chromosomal aberration involving NCOA1 is a cause of rhabdomyosarcoma. Translocation t(2;2)(q35;p23) with PAX3 generates the NCOA1-PAX3 oncogene consisting of the N-terminus part of PAX3 and the C-terminus part of NCOA1. The fusion protein acts as a transcriptional activator. Rhabdomyosarcoma is the most common soft tissue carcinoma in childhood, representing 5-8% of all malignancies in children. | ||
