3f92: Difference between revisions

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==Crystal structure of ubiquitin-conjugating enzyme E2-25kDa (Huntington Interacting Protein 2) M172A mutant crystallized at pH 8.5==
==Crystal structure of ubiquitin-conjugating enzyme E2-25kDa (Huntington Interacting Protein 2) M172A mutant crystallized at pH 8.5==
<StructureSection load='3f92' size='340' side='right' caption='[[3f92]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
<StructureSection load='3f92' size='340' side='right' caption='[[3f92]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3f92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3F92 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3f92]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3F92 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e46|3e46]], [[1yla|1yla]], [[1jbb|1jbb]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e46|3e46]], [[1yla|1yla]], [[1jbb|1jbb]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UBE2K, HIP2, LIG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/E2_ubiquitin-conjugating_enzyme E2 ubiquitin-conjugating enzyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.23 2.3.2.23] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitin--protein_ligase Ubiquitin--protein ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.19 6.3.2.19] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f92 OCA], [http://pdbe.org/3f92 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3f92 RCSB], [http://www.ebi.ac.uk/pdbsum/3f92 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3f92 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f92 OCA], [http://pdbe.org/3f92 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3f92 RCSB], [http://www.ebi.ac.uk/pdbsum/3f92 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: E2 ubiquitin-conjugating enzyme]]
[[Category: Ubiquitin--protein ligase]]
[[Category: Flatt, J W]]
[[Category: Flatt, J W]]
[[Category: Hughes, R C]]
[[Category: Hughes, R C]]
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[[Category: Twigg, P D]]
[[Category: Twigg, P D]]
[[Category: Wilson, R C]]
[[Category: Wilson, R C]]
[[Category: Alternative splicing]]
[[Category: Cytoplasm]]
[[Category: E2-25k]]
[[Category: E2-25k]]
[[Category: Hip-2]]
[[Category: Hip-2]]
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[[Category: Ubiquitin-conjugating enzyme e2 k]]
[[Category: Ubiquitin-conjugating enzyme e2 k]]
[[Category: Ubiquitin-protein ligase]]
[[Category: Ubiquitin-protein ligase]]
[[Category: Ubl conjugation]]
[[Category: Ubl conjugation pathway]]
[[Category: Ubl conjugation pathway]]
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