1xd2: Difference between revisions

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|PDB= 1xd2 |SIZE=350|CAPTION= <scene name='initialview01'>1xd2</scene>, resolution 2.70&Aring;
|PDB= 1xd2 |SIZE=350|CAPTION= <scene name='initialview01'>1xd2</scene>, resolution 2.70&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=GDP:GUANOSINE-5&#39;-DIPHOSPHATE'>GDP</scene>
|LIGAND= <scene name='pdbligand=GDP:GUANOSINE-5&#39;-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE= HRAS, HRAS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), SOS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= HRAS, HRAS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), SOS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[1nvv|1NVV]], [[1nvu|1NVU]], [[1nvw|1NVW]], [[1nvx|1NVX]], [[1bkd|1BKD]], [[1xd4|1XD4]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xd2 OCA], [http://www.ebi.ac.uk/pdbsum/1xd2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xd2 RCSB]</span>
}}
}}


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==Disease==
==Disease==
Known diseases associated with this structure: Bladder cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190020 190020]], Costello syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190020 190020]], Fibromatosis, gingival OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]], Noonan syndrome 4 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]], Thyroid carcinoma, follicular, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190020 190020]]
Known disease associated with this structure: Fibromatosis, gingival OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]], Noonan syndrome 4 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]]


==About this Structure==
==About this Structure==
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[[Category: Sondermann, H.]]
[[Category: Sondermann, H.]]
[[Category: Yang, S S.]]
[[Category: Yang, S S.]]
[[Category: GDP]]
[[Category: MG]]
[[Category: PO4]]
[[Category: ras-nucleotide exchange factor complex]]
[[Category: ras-nucleotide exchange factor complex]]
[[Category: ras:sos complex]]
[[Category: ras:sos complex]]


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