5ipp: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5ipp is ~~ON HOLD~~ ~~until Paper Publication~~

==Structure of Bacillus NanoRNase A active site mutant bound to a mononucleotide==

== Structural highlights ==

<table><tr><td colspan='2'>[[5ipp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPP OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IPP FirstGlance].

</td></tr><tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5iuf|5iuf]]</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/3'(2'),5'-bisphosphate_nucleotidase 3'(2'),5'-bisphosphate nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.7 3.1.3.7] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ipp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ipp OCA], [http://pdbe.org/5ipp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ipp RCSB], [http://www.ebi.ac.uk/pdbsum/5ipp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ipp ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/NRNA_BACSU NRNA_BACSU]] Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter, with a preference for 3-mers. Directionality is controversial; shown to degrade 5-mers and less in a 3' to 5' direction (PubMed:17586819), and 11-mers in a 5' to 3' direction (PubMed:21087930). Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP.<ref>PMID:17586819</ref> <ref>PMID:21087930</ref> <ref>PMID:22114320</ref>

~~Authors: Schmier, B.J., Nelersa, C.M., Malhotra, A.~~

==See Also==

*[[Ribonuclease|Ribonuclease]]

~~Description: Structure of Bacillus NanoRNase A active site mutant bound to a mononucleotide~~

== References ==

[[~~Category: Unreleased Structures~~]]

__TOC__

</StructureSection>

[[Category: Malhotra, A]]

[[Category: Schmier, B.J]]

[[Category: Nelersa, C M]]

[[Category: ~~Nelersa, C~~.M]]

[[Category: Schmier, B J]]

[[Category: Abortive transcript]]

[[Category: B. subitli]]

[[Category: Exonuclease]]

[[Category: Hydrolase]]

[[Category: Nanorna]]

[[Category: Pap phosphatase]]

[[Category: Rna degradation]]

[[Category: Rnase]]

[[Category: X-ray]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5ipp is ON HOLD  until Paper Publication
+==Structure of Bacillus NanoRNase A active site mutant bound to a mononucleotide==
+<StructureSection load='5ipp' size='340' side='right' caption='[[5ipp]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5ipp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IPP FirstGlance]. <br>
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5iuf|5iuf]]</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3'(2'),5'-bisphosphate_nucleotidase 3'(2'),5'-bisphosphate nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.7 3.1.3.7] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ipp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ipp OCA], [http://pdbe.org/5ipp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ipp RCSB], [http://www.ebi.ac.uk/pdbsum/5ipp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ipp ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/NRNA_BACSU NRNA_BACSU]] Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter, with a preference for 3-mers. Directionality is controversial; shown to degrade 5-mers and less in a 3' to 5' direction (PubMed:17586819), and 11-mers in a 5' to 3' direction (PubMed:21087930). Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP.<ref>PMID:17586819</ref> <ref>PMID:21087930</ref> <ref>PMID:22114320</ref>
-Authors: Schmier, B.J., Nelersa, C.M., Malhotra, A.
+==See Also==
+*[[Ribonuclease|Ribonuclease]]
-Description: Structure of Bacillus NanoRNase A active site mutant bound to a mononucleotide
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Malhotra, A]]
-[[Category: Schmier, B.J]]
+[[Category: Nelersa, C M]]
-[[Category: Nelersa, C.M]]
+[[Category: Schmier, B J]]
+[[Category: Abortive transcript]]
+[[Category: B. subitli]]
+[[Category: Exonuclease]]
+[[Category: Hydrolase]]
+[[Category: Nanorna]]
+[[Category: Pap phosphatase]]
+[[Category: Rna degradation]]
+[[Category: Rnase]]
+[[Category: X-ray]]