1ypl: Difference between revisions

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|PDB= 1ypl |SIZE=350|CAPTION= <scene name='initialview01'>1ypl</scene>, resolution 1.85&Aring;
|PDB= 1ypl |SIZE=350|CAPTION= <scene name='initialview01'>1ypl</scene>, resolution 1.85&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RA8:N-(BENZYLSULFONYL)-L-LEUCYL-N-(4-{[AMINO(IMINO)METHYL]AMINO}BUTYL)-L-PROLINAMIDE'>RA8</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RA8:N-(BENZYLSULFONYL)-L-LEUCYL-N-(4-{[AMINO(IMINO)METHYL]AMINO}BUTYL)-L-PROLINAMIDE'>RA8</scene>, <scene name='pdbligand=TYS:SULFONATED+TYROSINE'>TYS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span>
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=[[1ypm|1YPM]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ypl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypl OCA], [http://www.ebi.ac.uk/pdbsum/1ypl PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ypl RCSB]</span>
}}
}}


'''X-ray crystal structure of thrombin inhibited by synthetic cyanopeptide analogue RA-1008'''
'''X-ray crystal structure of thrombin inhibited by synthetic cyanopeptide analogue RA-1008'''


==Disease==
Known diseases associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]


==About this Structure==
==About this Structure==
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[[Category: Fokkens, J.]]
[[Category: Fokkens, J.]]
[[Category: Radau, G.]]
[[Category: Radau, G.]]
[[Category: GOL]]
[[Category: NA]]
[[Category: RA8]]
[[Category: 6 stranded beta-sheet]]
[[Category: 6 stranded beta-sheet]]
[[Category: barrel]]
[[Category: barrel]]
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[[Category: thrombin]]
[[Category: thrombin]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:25:52 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:17:01 2008''

Revision as of 22:17, 30 March 2008

File:1ypl.gif


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1ypl, resolution 1.85Å
Ligands: GOL, NA, RA8, TYS
Activity: Thrombin, with EC number 3.4.21.5
Related: 1YPM


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



X-ray crystal structure of thrombin inhibited by synthetic cyanopeptide analogue RA-1008


About this Structure

1YPL is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 01:17:01 2008

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