Virion infectivity factor

spinqualitylabelsall models HIV-1 virion infectivity factor (grey) complex with human elongin-B Green) and elongin-C (pink) (PDB code 2ma9) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Virion infectivity factor (Vif) of HIV-1 is essential for efficient viral replication by binding to the a component of the innate immune system and triggering its polyubiquitination and rapid degradation thus preventing its entry into progeny virions. For details see HIV and accessory proteins

3D Structures of virion infectivity factor

Updated on 16-October-2017

HIV and accessory proteins – Vif + cullin-5 + elongin-C + elongin-B + CBF-β – HIV-1
2ma9, 3dcg – Vif + elongin-C + elongin-B – HIV-1

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