5v6n: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 5v6n is ON HOLD until Paper Publication~~

==Crystal Structure of the highly open channel-stabilized mutant C27S + K33C + I9'A + N21'C of GLIC under reducing conditions.==

~~Authors: Gonzalez-Gutierrez, G., Grosman, C.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5v6n]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V6N OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V6N FirstGlance].

~~Description:~~ Crystal Structure of the highly open channel-stabilized mutant C27S + K33C + I9'A + N21'C of GLIC under reducing conditions.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5v6o|5v6o]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v6n OCA], [http://pdbe.org/5v6n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v6n RCSB], [http://www.ebi.ac.uk/pdbsum/5v6n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v6n ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Gonzalez-Gutierrez, G]]

[[Category: Grosman, C]]

[[Category: ~~Gonzalez~~-~~Gutierrez, G~~]]

[[Category: Cys-loop receptor]]

[[Category: Elic]]

[[Category: Glic]]

[[Category: Glucl]]

[[Category: Ion channel]]

[[Category: Membrane protein]]

[[Category: Metal transport]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5v6n is ON HOLD  until Paper Publication
+==Crystal Structure of the highly open channel-stabilized mutant C27S + K33C + I9'A + N21'C of GLIC under reducing conditions.==
+<StructureSection load='5v6n' size='340' side='right' caption='[[5v6n]], [[Resolution|resolution]] 3.35&Aring;' scene=''>
-Authors: Gonzalez-Gutierrez, G., Grosman, C.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5v6n]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V6N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V6N FirstGlance]. <br>
-Description: Crystal Structure of the highly open channel-stabilized mutant C27S + K33C + I9'A + N21'C of GLIC under reducing conditions.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5v6o|5v6o]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v6n OCA], [http://pdbe.org/5v6n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v6n RCSB], [http://www.ebi.ac.uk/pdbsum/5v6n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v6n ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Gonzalez-Gutierrez, G]]
 [[Category: Grosman, C]]
-[[Category: Gonzalez-Gutierrez, G]]
+[[Category: Cys-loop receptor]]
+[[Category: Elic]]
+[[Category: Glic]]
+[[Category: Glucl]]
+[[Category: Ion channel]]
+[[Category: Membrane protein]]
+[[Category: Metal transport]]