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Latest revision as of 14:43, 19 October 2017
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Function
Complement regulator-acquiring surface protein (CRASP) are proteins of the Lyme-disease causing bacteria Borrelia burgdorferi which bind to several human extracellular matrix proteins. For details on CRASP-1 see Borrelia burgdorferi Complement Regulator-Acquiring Surface Protein 1.[1][2]
Disease
Lyme-disease adhesion factors.
- ↑ Hallstrom T, Haupt K, Kraiczy P, Hortschansky P, Wallich R, Skerka C, Zipfel PF. Complement regulator-acquiring surface protein 1 of Borrelia burgdorferi binds to human bone morphogenic protein 2, several extracellular matrix proteins, and plasminogen. J Infect Dis. 2010 Aug 15;202(3):490-8. doi: 10.1086/653825. PMID:20565259 doi:10.1086/653825
- ↑ Brangulis K, Petrovskis I, Kazaks A, Bogans J, Otikovs M, Jaudzems K, Ranka R, Tars K. Structural characterization of CspZ, a complement regulator factor H and FHL-1 binding protein from Borrelia burgdorferi. FEBS J. 2014 Apr 7. doi: 10.1111/febs.12808. PMID:24702793 doi:https://dx.doi.org/10.1111/febs.12808
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3D structures of Complement regulator-acquiring surface protein
Updated on 19-October-2017
{"openlevels":0}
- CRASP-1
- CRASP-2
- 4bg0 – BbCRASP-2
- 4cbe – BbCRASP-2 residues 23-236
References
