Single-stranded DNA-binding protein: Difference between revisions
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<StructureSection load='1eqq' size='450' side='right' scene='' caption='E. coli SSB complex with ssDNA and UMP [[1eqq]]'> | <StructureSection load='1eqq' size='450' side='right' scene='' caption='E. coli SSB complex with ssDNA (stick model) and UMP [[1eqq]]'> | ||
'''Single-stranded DNA-binding protein''' (SSB) binds to single-stranded regions of DNA (ssDNA) to protect it from annealing, prevention of secondary structure formation and digestion. SSB binds to DNA in a sequence-independent manner. The binding of SSB enables processes like replication, DNA repair and recombination to occur. SSB can form complexes with specific genome maintenance proteins helping their activities<ref>PMID:22976174</ref>.<br /> | '''Single-stranded DNA-binding protein''' (SSB) binds to single-stranded regions of DNA (ssDNA) to protect it from annealing, prevention of secondary structure formation and digestion. SSB binds to DNA in a sequence-independent manner. The binding of SSB enables processes like replication, DNA repair and recombination to occur. SSB can form complexes with specific genome maintenance proteins helping their activities<ref>PMID:22976174</ref>.<br /> | ||
* '''Viral SSB proteins''' are monomeric.<br /> | * '''Viral SSB proteins''' are monomeric.<br /> | ||
