5vkg: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5vkg is ~~ON HOLD~~ ~~until Paper Publication~~

==Solution-state NMR structural ensemble of human Tsg101 UEV in complex with tenatoprazole==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5vkg]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VKG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VKG FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4N1:4-methoxy-1-(5-methoxy-3H-imidazo[4,5-b]pyridin-2-yl)-3,5-dimethyl-2-(sulfanylmethyl)pyridin-1-ium'>4N1</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vkg OCA], [http://pdbe.org/5vkg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vkg RCSB], [http://www.ebi.ac.uk/pdbsum/5vkg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vkg ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/TS101_HUMAN TS101_HUMAN]] Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.<ref>PMID:11916981</ref> <ref>PMID:17853893</ref> <ref>PMID:17556548</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Carter, C]]

[[Category: Ehrlich, L S]]

[[Category: Khan, M]]

[[Category: Leis, J]]

[[Category: Luan, C H]]

[[Category: Powell, M D]]

[[Category: Strickland, M]]

[[Category: Strub, M P]]

[[Category: Tjandra, N]]

[[Category: Watanabe, S]]

[[Category: Cell cycle]]

[[Category: Cell cycle-inhibitor complex]]

[[Category: Escrt-i]]

[[Category: Inhibitor]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5vkg is ON HOLD  until Paper Publication
+==Solution-state NMR structural ensemble of human Tsg101 UEV in complex with tenatoprazole==
+<StructureSection load='5vkg' size='340' side='right' caption='[[5vkg]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5vkg]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VKG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VKG FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4N1:4-methoxy-1-(5-methoxy-3H-imidazo[4,5-b]pyridin-2-yl)-3,5-dimethyl-2-(sulfanylmethyl)pyridin-1-ium'>4N1</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vkg OCA], [http://pdbe.org/5vkg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vkg RCSB], [http://www.ebi.ac.uk/pdbsum/5vkg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vkg ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TS101_HUMAN TS101_HUMAN]] Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.<ref>PMID:11916981</ref> <ref>PMID:17853893</ref> <ref>PMID:17556548</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Carter, C]]
+[[Category: Ehrlich, L S]]
+[[Category: Khan, M]]
+[[Category: Leis, J]]
+[[Category: Luan, C H]]
+[[Category: Powell, M D]]
+[[Category: Strickland, M]]
+[[Category: Strub, M P]]
+[[Category: Tjandra, N]]
+[[Category: Watanabe, S]]
+[[Category: Cell cycle]]
+[[Category: Cell cycle-inhibitor complex]]
+[[Category: Escrt-i]]
+[[Category: Inhibitor]]