5gxe: Difference between revisions
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==Crystal structure of Acryloyl-CoA reductase AcuI in complex with NADPH== | |||
<StructureSection load='5gxe' size='340' side='right' caption='[[5gxe]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5gxe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ruepo Ruepo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GXE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GXE FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5gxf|5gxf]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">acuI, SPO1914 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=246200 RUEPO])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.84 1.3.1.84] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gxe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gxe OCA], [http://pdbe.org/5gxe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gxe RCSB], [http://www.ebi.ac.uk/pdbsum/5gxe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gxe ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ACUI_RUEPO ACUI_RUEPO]] Probably catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA. Restores acrylate resistance when expressed in an E.coli strain K12 acuI deletion.<ref>PMID:22563425</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Oxidoreductase]] | |||
[[Category: Ruepo]] | |||
[[Category: Cao, H Y]] | |||
[[Category: Wang, P]] | |||
[[Category: Zhang, Y Z]] | |||
[[Category: Acryloyl-coa]] | |||
[[Category: Acui]] | |||
[[Category: Reductase]] | |||
Revision as of 14:10, 15 November 2017
Crystal structure of Acryloyl-CoA reductase AcuI in complex with NADPH
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