5d3o: Difference between revisions
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==Crystal structure of full length human glutaminase C expressed in E.coli== | |||
<StructureSection load='5d3o' size='340' side='right' caption='[[5d3o]], [[Resolution|resolution]] 2.79Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5d3o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D3O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D3O FirstGlance]. <br> | |||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLS, GLS1, KIAA0838 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaminase Glutaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.2 3.5.1.2] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d3o OCA], [http://pdbe.org/5d3o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d3o RCSB], [http://www.ebi.ac.uk/pdbsum/5d3o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d3o ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN]] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Glutaminase]] | |||
[[Category: Human]] | |||
[[Category: Huang, Q]] | [[Category: Huang, Q]] | ||
[[Category: Gac]] | |||
[[Category: Glutaminase c]] | |||
[[Category: Hydrolase]] | |||
Revision as of 16:43, 15 November 2017
Crystal structure of full length human glutaminase C expressed in E.coli
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