5uvz: Difference between revisions
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==BRD4 Bromodomain 2 with A-1354689== | |||
<StructureSection load='5uvz' size='340' side='right' caption='[[5uvz]], [[Resolution|resolution]] 1.63Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5uvz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UVZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UVZ FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8NP:3-methyl-5-(2-phenoxyphenyl)pyridin-2(1H)-one'>8NP</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5uvs|5uvs]], [[5uvu|5uvu]], [[5uvt|5uvt]], [[5uvv|5uvv]], [[5uvx|5uvx]], [[5uvy|5uvy]], [[5uvw|5uvw]]</td></tr> | ||
[[Category: Park, C | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uvz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uvz OCA], [http://pdbe.org/5uvz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uvz RCSB], [http://www.ebi.ac.uk/pdbsum/5uvz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uvz ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity). | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human]] | |||
[[Category: Park, C H]] | |||
[[Category: Helix bundle]] | |||
[[Category: Signaling protein-inhibitor complex]] | |||
Revision as of 10:01, 16 November 2017
BRD4 Bromodomain 2 with A-1354689
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