5x3t: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5x3t is ~~ON HOLD~~ ~~until Paper Publication~~

==VapBC from Mycobacterium tuberculosis==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5x3t]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X3T OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X3T FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">vapB26, Rv0581 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU]), vapC26, Rv0582 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x3t OCA], [http://pdbe.org/5x3t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x3t RCSB], [http://www.ebi.ac.uk/pdbsum/5x3t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x3t ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/VPB26_MYCTU VPB26_MYCTU]] Antitoxin component of a type II toxin-antitoxin (TA) module. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC26.<ref>PMID:20011113</ref> [[http://www.uniprot.org/uniprot/VPC26_MYCTU VPC26_MYCTU]] Toxic component of a type II toxin-antitoxin (TA) module. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB26.[HAMAP-Rule:MF_00265]<ref>PMID:20011113</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Myctu]]

[[Category: Kang, S M]]

[[Category: Kim, D H]]

[[Category: Lee, B J]]

[[Category: Yoon, H J]]

[[Category: Antitoxin-toxin complex]]

[[Category: Ribonuclease]]

[[Category: Ta system]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5x3t is ON HOLD  until Paper Publication
+==VapBC from Mycobacterium tuberculosis==
+<StructureSection load='5x3t' size='340' side='right' caption='[[5x3t]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5x3t]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X3T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X3T FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vapB26, Rv0581 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU]), vapC26, Rv0582 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x3t OCA], [http://pdbe.org/5x3t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x3t RCSB], [http://www.ebi.ac.uk/pdbsum/5x3t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x3t ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/VPB26_MYCTU VPB26_MYCTU]] Antitoxin component of a type II toxin-antitoxin (TA) module. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC26.<ref>PMID:20011113</ref>  [[http://www.uniprot.org/uniprot/VPC26_MYCTU VPC26_MYCTU]] Toxic component of a type II toxin-antitoxin (TA) module. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB26.[HAMAP-Rule:MF_00265]<ref>PMID:20011113</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Myctu]]
+[[Category: Kang, S M]]
+[[Category: Kim, D H]]
+[[Category: Lee, B J]]
+[[Category: Yoon, H J]]
+[[Category: Antitoxin-toxin complex]]
+[[Category: Ribonuclease]]
+[[Category: Ta system]]